HTG Releases Proof-of-Approach Whitepaper Establishing Utility of Transcriptome… – Press Release

[ad_1]

TUCSON, Ariz., March 31, 2022 (GLOBE NEWSWIRE) — HTG Molecular Diagnostics, Inc. HTGM (HTG), a life science company advancing precision medicine through its innovative transcriptome-wide profiling technology, has released its first proof-of-approach white paper (the “White Paper”), establishing the utility of its novel approach to drug discovery utilizing its proprietary platform.

“The need to accelerate the drug discovery process so that innovative new treatments reach patients as quickly as possible cannot be overstated,” said Dr. Stephen Barat, Senior Vice President of Therapeutics at HTG. “We believe our technology provides a critical component to reaching that urgent goal, with the results of this study providing early and exciting substantiation of the opportunity presented by a transcriptome-informed approach to early-stage drug discovery.”

A cornerstone of HTG’s Therapeutics business, the HTG Transcriptome Panel (HTP) was launched with commercial availability in August of 2021. The HTP was designed to enable the assessment of approximately 20,000 mRNA targets using HTG’s EdgeSeq technology, a targeted RNA sequencing technology that couples a nuclease protection assay with next-generation sequencing for rapid and accurate RNA quantification. HTG EdgeSeq’s many advantages include a 96-well plate format, low sample input requirement, no RNA extraction, and rapid assay and analysis time – making it a particularly attractive technology for applying transcriptomic profiling to drug discovery.

The newly released White Paper establishes the utility of the HTP in transcriptome-informed drug discovery by way of an initial proof-of-concept experiment. The ability to profile the entire human transcriptome, with a high degree of reproducibility enabling screening using a single sample, a low amount of sample material required, and improved resolution for the detection of differentially expressed genes are some of the key benefits that differentiate the HTP from other…

[ad_2]